Nanjing Chemical Material Corp.
Service
Products

The Role of Dipotassium Glycyrrhizinate in Cosmetics The Role of Dipotassium Glycyrrhizinate in Cosmetics

Table of Content [Hide]

    With the advent of autumn, ultraviolet rays are no longer as strong as summer, which is a good time for skin whitening and skin care. So, how to choose pure natural whitening products with good effects?


    Ⅰ. About Dipotassium Glycyrrhizinate


    Dipotassium glycyrrhizinate is an organic compound. It is a white or off-white fine powder with a purity of 98%. It has a special sweetness, good solubility in water and a pure taste. Dipotassium glycyrrhizinate has many functions such as antibacterial, anti-inflammatory, detoxification, anti-allergic, deodorizing, etc., and has a wide range of applications in medicine, cosmetics, daily chemical, food and other industries. Dipotassium Glycyrrhizinate is one of the herbal extracts, which is refined from the effective ingredients extracted from licorice. Licorice is a perennial herb, the plant is about 1 to 1.5 meters high, the leaves are small and dark green, the flowers are yellow, blue, and violet, and the rhizomes have a sweet taste. Licorice is a traditional Chinese herbal medicine with phlegm-reducing, moisturizing, anti-inflammatory, anti-filtering pathogen, anti-hepatic toxin and anti-bacterial effects.


    Ⅱ. The role of dipotassium glycyrrhizinate in cosmetics


    Dipotassium glycyrrhizinate can penetrate deep into the skin and maintain high activity, whitening and effective anti-oxidation. Dipotassium glycyrrhizinate can effectively inhibit the activity of various enzymes in the process of melanin production, especially the activity of tyrosine, so that it cannot stimulate melanocytes to secrete melanin; it also has the effects of preventing skin roughness and anti-inflammatory and antibacterial. Dipotassium glycyrrhizinate is currently a whitening ingredient with good curative effects and comprehensive functions. Dipotassium Glycyrrhizinate is a whitening cosmetic additive launched by Japanese company MARUZEN in 1989. And then pharmaceutical raw materials suppliers started to add it into the cosmetics. After years of use, it has obvious effects and good safety. It is currently the main functional ingredient of high-end whitening cosmetics in the world.


    Ⅲ. The whitening principle of dipotassium glycyrrhizinate


    1. Inhibit the generation of reactive oxygen species: Dipotassium glycyrrhizinate is a flavonoid compound with strong antioxidant activity. Some researchers used superoxide dismutase SOD as a control group, and the results showed that dipotassium glycyrrhizinate can effectively inhibit the production of reactive oxygen species.


    2. Inhibition of tyrosinase: Compared with commonly used whitening materials, the inhibition IC50 of tyrosinase of dipotassium glycyrrhizinate is very low. Dipotassium glycyrrhizinate is recognized as a strong tyrosinase inhibitor, which is better than some commonly used raw materials.


    3. Inhibit melanin production: choose the back skin of guinea pigs, under UVB irradiation, the skin pretreated with 0.5% dipotassium glycyrrhizinate has a higher white coefficient (L value) than the control skin, and the effect is significant. The experimental results show that licorice Dipotassium acid can significantly inhibit the production of melanin. Dipotassium glycyrrhizinate can be used to prevent skin pigmentation and melanin production after sun exposure.

    References
    Related News
    • Live Up to the Spring and Steadily Progress丨2023 NCMC Annual Meeting Successfully Held!

      Live Up to the Spring and Steadily Progress丨2023 NCMC Annual Meeting Successfully Held!

      July 29, 2024Stay true to the mission and pursue our dream.In the beginning of 2024, NCMC held its annual meeting and celebration as scheduled, all NCMCer gathered together to look back on 2023 and look forward to...view
    • 79th API China

      79th API China

      January 31, 2018November 15-17, 2017Xiamen International Convention and Exhibition CenterAPI China is China's leading exhibition for the pharmaceutical manufacturing sector covering the complete spectrum of products ...view
    • Application of Potassium Iodide in Medicine

      Application of Potassium Iodide in Medicine

      October 9, 2021Potassium iodide is a colorless cube crystal, in the form of particles or powders, and it has deliquescence so when it is exposed to the air for a long time, iodine will dissociate and turn to yellow....view
    • Fully Refined Paraffin Wax

      Fully Refined Paraffin Wax

      July 20, 2021Fully Refined Paraffin Wax is a white, cream, yellow or colorless soft solid derivable from petroleum, paraffin wax is a mixture of hydrocarbon molecules containing between twenty and forty carbon ato...view
    • Application of Glycolic Acid in Leather Industry

      Application of Glycolic Acid in Leather Industry

      October 9, 2021Ⅰ. Glycolic acid for leather dyeing and tannage:Glycollic acid is used as the dyeing and tanning agent in the leather industry to improve the quality of products. Reasons are as following:1. Its effe...view
    • Principle of Surface Tension Reduction by Surfactants

      Principle of Surface Tension Reduction by Surfactants

      March 4, 2021In order to reduce the surface tension of water, for example, the surfactant molecules have hydrophilic and lipophilic groups. Due to the repulsion between the lipophilic groups and the water molecule...view
    • TEL:+86-25-52337978
    • EMAIL: info@njchm.com
    • ADDRESS:12/F, Block B, Technology and Innovation Building, Nanjing University of Technology, No.5 New Model Road, Nanjing 210009, China